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A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis

Supplements Vitamin B 12 is available over-the-counter as a single-nutrient supplement and also as a component of multivitamin and vitamin B-complex supplements (129)

Research suggests it may act through beta-3 adrenergic pathways or through non-receptor-mediated effects on adipocyte lipid metabolism, rather than through classical GH receptor signaling